Anti-ganglioside asialo GM2 is very useful in the identification of ganglioside asialo GM2 and in immunotargeting cells expressing asialo GM2. Several gangliosides have been found to have an elevated expression in tumor cells. Many therapeutic treatments of tumor cells are being investigated using antibodies to target cells that express these elevated levels of gangliosides. Lymphoma has been shown to have an increased level of asialo GM2 and passive immunization with monoclonal immunoglobulin G3 antibodies to asialo GM2 has effectively suppressed tumor formation in these cells.3 Asialo- GM2 has been identified as a receptor for many types of bacteria including Neisseria gonorrhoeae and Haemophilus influenzae.
