- 中文名称
2-乙酰基-4-（1R，2S，3R，4-四羟基丁基）-咪唑
- 英文名字
- 2-Acetyl-4-(1R, 2S, 3R, 4-tetrahydroxybutyl)-imidazole
- 供应商
- Matreya
- 产品货号
- 1858-1
- 产品报价
- ￥询价/1mg
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- 2-Acetyl-4-(1R,2S,3R,4-tetrahydroxybutyl)-imidazole (THI) is an inhibitor of sphingosine-1-phosphate lyase (S1P lyase). In high doses it leads to the inhibition of S1P lyase, causing an accumulation of sphingosine-1-phosphate and a decrease in the activity of sphingosine-1-phosphate receptor-1. This results in lymphopenia (depression of blood lymphocyte counts) as well as an immune deficiency.1 THI does not appear to have any toxic effects and may therefore be valuable as an immunosuppressive drug. Diabetes can occur spontaneously due to autoimmune insulitis and THI has been proposed as a possible treatment for the prevention of this disease.2 It is thought that THI and Pyridoxine (vitamin B6) may compete for the same binding site as an additional diet of pyridoxine can prevent the decrease of blood lymphocyte counts caused by THI. THI has a structural similarity to histamine and urocanic acid, both known to have immunosuppressive properties.3 THI is a minor component of the food additive caramel color III.
- 产品描述
- 2-Acetyl-4-tetrahydroxybutylimidazole (THI)|Activity: Sphingosine-1-phosphate lyase inhibitor
- 产品形式
- 该2-乙酰基-4-（1R，2S，3R，4-四羟基丁基）-咪唑产品为固体形式
- 保存建议
- 对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明书。
- 其他
- Matreya LLC是一家脂质生化公司，致力于开发和制造高质量的脂质和生物化学品。Matreya在化学合成以及天然产物提取和纯化方面经验丰富，生产出的产品具有最佳纯度。 Matreya产品线包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和维生素E异构体（生育酚和生育三烯酚）。专长是生产高纯度鞘氨醇、神经酰胺、硫酸酯、神经节苷脂、酶抑制剂、生育酚和生育三烯酚。是全球提供脂质产品最全的供应商之一。产品涉及生物化学、制药、微生物学、食品和农业等研究领域。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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