Omega-oxidation is a minor fatty acid pathway used for fatty acid metabolism and usually occurs in the smooth endoplasmic reticulum. Docosanoic acid is enzymaticaly converted to the 22-hydroxydocosanoic acid as well as to the docosanoic dicarboxylic acid as part of the omega-oxidation metabolic pathway.1 22-Hydroxydocosanoic acid is the major aliphatic constituent of green cotton fibers but a very minor component of white cotton fibers.2 Stimulation of omega-hydroxylation has been proposed as a method for treating X-linked adrenoleukodystrophy, a disease that is characterized by elevated levels of very long chain fatty acids.3
