e kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. Based upon their structures and sequence relationships， ephrins are divided into the ephrin-A （EFNA） class， which are attached to the membrane by a glycosylphosphatidylinositol linkage， and the ephrin-B （EFNB） class， which are transmembrane proteins. Class A ephrins are linked to the membrane by a GPI linkage and bind primarily to EphA receptors； Class B ephrins contain a membrane-spanning region and bind primarily to EphB receptors. Both ephrins and Eph receptors are largely expressed throughout the ectoderm， mesoderm， and endoderm of vertebrate embryos.
EFNB3 is a member of the ephrin gene family.
EFNB3 is significant in brain development as well as in its maintenance.
Furthermore， since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions， it may play a key role in forebrain function.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered clear solution. Ephrin B3 in 50mM Tris-Acetate， pH7.5， 1mM EDTA and 20% Glycerol.
保存建议
Store vial at -20℃ to -80℃. When stored at the recommended temperature， this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
