This is a personalized conjugation kit (PerKit™) developed for labeling any IgG type antibody with small molecules containing carboxylic acid (-COOH) functional groups. Using the kit components, the customer converts the carboxylic acid to an activated N-hydroxysuccinimide (NHS) ester, followed by a reaction with the surface amine groups of the protein to form a stable amide bond. The final product is then purified to remove any unreacted small molecule acid.
This kit provides materials to label 1-3 mg of one IgG type antibody with a small molecule acid.
