Acetylation of proteins can occur as a co-translational or post-translational modification (PTM) (1). Co-translational acetylation occurs at the N-terminal of approximately 93% of mammalian proteins, it is irreversible and is thought to be important i
产品描述
As part of the Signal-Seeker™ product line, AAC04 acetyl-lysine affinity beads have been optimized to detect endogenous levels of lysine-acetylated proteins. Acetyl-lysine affinity beads comprise a proprietary mixture of two anti-acetyl lysine antibodies (Clones 7B5A1 and 10C4B2.1) that has been chemically conjugated to Protein G beads. Validation studies have shown that these beads can immunoprecipitate a wide range of lysine-acetylated proteins with minimal detectable leaching of either heavy or light chains in an IP assay. A comprehensive Signal-Seeker™ acetyl-lysine Detection Kit is also available (BK163) and is recommended for first time users.
