Palmitoyl ethanolamide (PEA) is an endogenous cannabinoid found in brain, liver, and other mammalian tissues. PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activity in vitro. PEA is an endocannabinoid which has been shown to significantly elevate cAMP in cells expressing CB2 receptors. However, its affinity for CB2 receptors is relatively low, at about 10 uM. CB1 receptors have no appreciable affinity for PEA.
产品描述
An endogenous CB found in brain, liver, and other mammalian tissues found to have anti-anaphylactic and anti-inflammatory activity in vitro; an endocannabinoid that significantly elevates cAMP in cells expressing CB2 receptors; demonstrates low affinity for the CB2 receptor, at about 10 uM, and no appreciable affinity for the CB1 receptor