17-Octadecynoic Acid (17-ODYA) is a fatty acid analog with an .omega.-terminal acetylene. It is a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 ω-hydroxylase. At a concentration of 10 uM, 17-ODYA completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells.
产品描述
A suicide inhibitor of LTB4 20-hydroxylase and renal CYP450 ω-hydroxylase