Arachidonoyl glycine （N-arachidonyl glycine； NAGly） has been isolated from cell cultures treated with arachidonoyl ethanolamide （AEA； anandamide）， from extracts of mammalian brain， and has also been synthesized as an analog of AEA for structure/activity testing. NAGly may be produced endogenously via oxidation of AEA， or by transacylation of arachidonoyl CoA. NAGly is reported to have analgesic activities in whole animal experiments. Since it seems to be a very poor ligand for the CB1 receptor， these effects are probably mediated via other signaling pathways.
产品描述
Produced endogenously via oxidation of AEA， or by transacylation of arachidonoyl CoA； has analgesic activities in whole animal experiments， yet is a very poor ligand for the CB1 receptor
