S-Adenosylhomocysteine-d4 （SAH-d4） contains four deuterium atoms at the 3， 3’， 4， and 4’ positions. It is intended for use as an internal standard for the quantification of SAH by GC- or LC-mass spectrometry （MS）. S-Adenosyl-L-homocysteine （SAH） is an amino acid derivative and an intermediate， by-product， or modulator of several metabolic pathways， including the activated methyl cycle and cysteine biosynthesis. It is also a product of S-adenosyl-methionine （SAM）-dependent methylation of biological molecules， including DNA， RNA， and histones and other proteins. SAH is a risk factor for many diseases， including cancer and neurodegenerative diseases. In addition， inhibitors that block its hydrolysis are being developed as anti-viral， anti-parasitic， anti-arthritic and immunosuppressive agents.
产品描述
An internal standard for the quantification of SAH by GC- or LC-MS
