Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes， terpenoids， and sterols. It also serves as a donor in post-translational isoprenylation of proteins. FPP has been identified as an antagonist of P2Y12 receptors （IC50 = 45 uM）， attenuating platelet aggregation. It has also been shown to regulate adipocyte function as an endogenous PPARγ agonist. Additionally， because of a flexible hydrocarbon chain that enables different conformations， FPP is a promiscuous ligand for a subset of nuclear receptors.
产品描述
An intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes， terpenoids， and sterols； also serves as a donor in post-translational isoprenylation of proteins
