Guanylyl imidodiphosphate is a nonhydrolyzable analog of GTP that can bind to and irreversibly activate G proteins in the presence of Mg2+.{27512} This nucleotide is a potent stimulator of adenylate cyclase.{27510} Guanylyl imidodiphosphate is used in studies of protein synthesis since the process of GTP binding, hydrolysis, and release is essential for the initiation of protein translocation across the endoplasmic reticulum.{27511}
产品描述
A nonhydrolyzable GTP analog that binds to and irreversibly activates G proteins; potently stimulates adenylate cyclase