中文名称

NSC 58973；4-羟基-2-喹啉羧酸

英文名字

NSC 58973; 4-hydroxy-2-quinolinecarboxylic acid

供应商

Cayman Chemical

产品货号

16792-500

产品报价

￥询价/500mg

产品说明书

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购买方式

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产品新闻

背景资料

Kynurenic acid is a natural metabolite of tryptophan via the kynurenine pathway. It has pronounced effects on neuronal signaling and, thus, impacts diverse neurological systems.{27403,27404} Kynurenic acid broadly antagonizes ionotopic glutamate receptors at high micromolar to millimolar concentrations and is used to pharmacologically block the activation of these receptors in vivo or in vitro.{27407} In addition, it reportedly has more potent effects at glutamate receptor subunit ζ-1 (Ki = 5.4 µM), GPR35 (EC50 = 39 µM), aryl hydrocarbon receptor (EC50 = 300 nM), and neuronal acetylcholine receptor α-7 (IC50 = 7 µM).{27405,14771,27406,27404}

产品描述

A metabolite of tryptophan that has pronounced effects on neuronal signaling; broadly antagonizes ionotopic glutamate receptors; has potent effects at glutamate receptor subunit ζ-1 (Ki = 5.4 µM), GPR35 (EC50 = 39 µM), aryl hydrocarbon receptor (EC50 = 300 nM), and neuronal acetylcholine receptor α-7 (IC50 = 7 µM)

产品形式

A crystalline solid

保存建议

建议您在收到Cayman Chemical品牌的Kynurenic Acid​ (500 mg)产品后置于-20度保存，产品有效期为730天.

其他

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

注意

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