中文名称

神经节苷脂B1 |神经节苷脂G3；神经节苷脂GD1a，四钠盐

英文名字

Ganglioside B1|Ganglioside G3; Ganglioside GD1a, tetrasodium salt

供应商

Cayman Chemical

产品货号

15585-5

产品报价

￥询价/5mg

产品说明书

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购买方式

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产品新闻

背景资料

Gangliosides are formed from a glycosphingolipid combined with one or more sialic acids at the oligosaccharide chain. They are components of the plasma membrane where they pack densely with cholesterol to form lipid microdomains that modulate both intra- and inter-cell signaling events. More than 180 gangliosides have been identified, each of which differ based on the position and number of sialic acid residues. Ganglioside GD1a contains one sialic residue linked to the inner galatose unit and can be found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. At 20 μM, GD1a has been shown to increase endothelial cell proliferation.{25490} Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for TLR2, enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin.{25484}

产品描述

A glycosphingolipid that contains one sialic residue linked to the inner galatose unit; influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis; acts as a functional coreceptor for TLR2, enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin

产品形式

A lyophilized powder

保存建议

建议您在收到Cayman Chemical品牌的Ganglioside GD1a (sodium salt) (5 mg)产品后置于-20度保存，产品有效期为730天.

其他

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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