中文名称

24-脱氢胆固醇| NSC 226126; （3β）-cholesta-5,24-dien-3-ol

英文名字

24-dehydro Cholesterol|NSC 226126; (3β)-cholesta-5,24-dien-3-ol

供应商

Cayman Chemical

产品货号

14943-10

产品报价

￥询价/10mg

产品说明书

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购买方式

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产品新闻

背景资料

Desmosterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies.{26099} During brain development, desmosterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols.{26098} However, defects in cholesterol synthesis can lead to desmosterolosis, resulting from an accumulation of excess desmosterol.{26100} Desmosterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions.{26096,26097}

产品描述

An immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis; reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions

产品形式

A crystalline solid

保存建议

建议您在收到Cayman Chemical品牌的Desmosterol (10 mg)产品后置于-20度保存，产品有效期为730天.

其他

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

注意

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