- 中文名称
10-硝基-9,12-十八碳二烯酸| LNO2; 10-硝基-9E，12Z-十八碳二烯酸
- 英文名字
- 10-nitro-9,12-Octadecadienoic Acid|LNO2; 10-nitro-9E,12Z-octadecadienoic acid
- 供应商
- Cayman Chemical
- 产品货号
- 10037-1
- 产品报价
- ￥询价/1mg
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- 10-Nitrolinoleate is the product of nitration of linoleate by NO-derived reactive species.{25769,11912} Other nitrolinoleates detected in human plasma and urine include 9-, 12-, and 13-nitrolinoleate.{25770} Nitrolinoleates activate peroxisome proliferator-activated receptor γ (PPARγ; Ki = 133 nM), inducing CD36 expression in macrophages, adipocyte differentiation, and glucose uptake.{14255,13284} Nitrolinoleates can also be metabolized by smooth muscle cells to produce nitrite derivatives which in turn form NO, leading to increased cGMP production and smooth muscle relaxation.{11912,13287} Through the same mechanism, nitrolinoleate-derived NO suppresses leukocyte adhesion, in part through nitrosation of CD40.{25768} Alteratively, nitrolinoleates can act independently of NO/cGMP and PPARγ signaling to suppress neutrophil and macrophage functions.{25769,25770,14473}
- 产品描述
- The product of nitration of linoleate by NO-derived reactive species; activates PPARγ (Ki = 133 nM), inducing CD36 expression in macrophages, adipocyte differentiation, and glucose uptake; can also be metabolized to produce nitrite derivatives which in turn form NO, leading to increased cGMP production
- 产品形式
- A solution in ethanol
- 保存建议
- 建议您在收到Cayman Chemical品牌的10-Nitrolinoleate (1 mg)产品后置于-20度保存，产品有效期为365天.
- 其他
- Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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