- 中文名称
MOB2多克隆抗体
- 英文名字
- MOB2 Polyclonal Antibody
- 供应商
- Reddot Biotech
- 产品货号
- RD219976A
- 产品报价
- ￥询价/20uL ￥询价/60uL ￥询价/120uL ￥询价/200uL
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- 该MOB2 Polyclonal Antibody. MOB2 (Mps one binder kinase activator-like 2), also known as HCCA2 (Hepatocellular carcinoma-associated gene 2), is a 467 amino acid protein that belongs to the MOB1/phocein family. MOB2 is expressed in lung, spleen, brain, and fetal liver. It is highly expressed in hepatocellular carcinoma. MOB2 is localized in the perinuclear region of the cytoplasm in liver cancer tissues and colocalizes with MAD2L2 in the nucleus of Hela cells. MOB2 is characterized by two N-glycosylation sites, six N-myristolylation sites, two Src homology 3 (SH3), and several phosphorylation motifs which indicate that this protein may play a role in an intracellular signal transduction cascade. MOB2 binds to and regulates the autophosphorylation of the related human serine/threonine kinase 38 (NDR1) and serine/threonine kinase 38L(NDR2). It has been shown that MOB2 plays a critical role in cell cycle regulation. Overexpression of the protein during the G0/G1 phase inhibits cell proliferation causing cell cycle arrest. Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.
- 应用类型
- IHC,ELISA
- 免疫原
- Synthetic peptide of human MOB2
- 来源宿主
- 兔
- 反应性
- 人, 小鼠
- 保存建议
- 储存于-20 ℃。 避免冻融循环。
- 其他
- Reddot Biotech是由一支拥有35年医疗管理经验团队创办的加拿大本土品牌，其已在ELISA产品线上深耕7个年头，并且仍在不断前进中。产品的质量保证也让其越来越多被“收纳进”文献当中，产品线包括ELISA试剂盒、抗体、少量生化试剂，其中ELISA试剂盒超过6000+，物种类型较多：人；大鼠；小鼠；犬科类；牛科；鱼；鸡；猪；兔；山羊；绵羊；猿；马；豚鼠等，像激素类指标促卵泡素（FSH）、促黄体激素（LH），新冠相关病毒受体ACE2、ACE以及肿瘤免疫相关的指标精氨酸酶（ARG）等已是热门应用指标。
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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