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中文名称

Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)

英文名字
Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)
供应商
USBiological
产品货号
P9099-05
产品报价
¥1/1Kit
产品说明书
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产品新闻
背景资料
USBiological品牌是全球有名的抗原抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理,是行业中少有的致力于服务客户,帮助客户,且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应,专业的产品和解决方案支持,稳健快捷的交货周期,优质放心的售后服务。我们致力于为您提供有价值的产品和服务,在意您的成功!
产品描述
The United States Biological Proteinase-3, Human, BioAssay ELISA Kit is intended for the detection and semi-quantitative determination of antibodies to PR-3 in human serum. The assay is to be used to detect antibodies in a single serum specimen. Proteinase-3 is a lysosomal enzyme that can be found in human neutrophils. There are two subsets of autoantibodies to sample neutrophils, c- ANCA and p-ANCA. The first subtype, c-ANCA, shows cytoplasmic staining by IFA and is diagnostic for Wegener's granulomatosis. The major antigen responsible for the c-ANCA staining is Proteinase-3. The second subtype, p- ANCA, shows perinuclear staining by IFA. The major antigen responsible for the p-ANCA response has been shown to be myeloperoxidase. The ANCA staining patterns are obtained using ethanol-fixed sample neutrophils. Anti- PR-3 autoantibodies have been associated with Wegener's granulomatosis but less often with microscopic polyangiitis. Other antigen specificity's (CAP 57) can be responsible for the c-ANCA pattern. These antigens are generally not diagnostic for PR-3 associated vaculitus diseases. Kit Components:Each kit contains the following components in sufficient quantities to perform the number of tests indicated on the package label.1. Microtiter Plate: 1x96 wells2. Sample Diluent: 1x30ml3. Positive Control, High: 1x400ul4. Calibrator: 1x400ul5. Negative Control: 1x400ul6. Positive Control, Low: 1x400ul7. IgG, IgA, IgM (HRP) Goat x human: 1x15ml8. Wash Buffer, 20X: 1x50ml9. Tetramethylbenzidine (TMB): 1x15ml10. Stop Solution: 1x15ml Storage and Stability:Store all components at 4°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
产品特点
针对Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)该产品的特点优势,欢迎查阅官网提供的产品说明书。
保存建议
建议收到Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)产品后将其置于4°C保存。
其他
Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研用户提供了诸多超值选择。
注意
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