This pseudovirus is a BSL-1 baculovirus vector pseudotyped with Spike proteins, in this case the Spike protein originally sequenced from isolates obtained in Wuhan. Biologists and drug discovery teams can use this reagent to work on COVID-19 projects outside of BSL-3 facilities with standard safety procedures. Once inside the cell, the pseudovirus does not replicate, but delivers a genetically-encoded, fluorescent reporter that expresses bright green fluorescence in the host cell nucleus. If needed, cellular entry can be facilitated with ACE2 and other proteins packaged in BacMam and available from Montana Molecular. 5mL and 30mL sizes are also available. This kit includes the pseudovirus and 500mM sodium butyrate in H2O.
