Montana Molecular红核靶向cADDis cAMP：实时监测细胞核内信号活动

用荧光成像监测细胞核中cAMP的变化。基因编码并包装在BacMam病毒载体中，可轻松转导到多种细胞类型中，包括原代和iPSC衍生的细胞系。绿色荧光核靶向cAMP传感器也是可用的。

艾美捷 Montana Molecular红核靶向cADDis cAMP#U0211R包含的材料：

红色核靶向cADDis cAMP传感器BacMam

丁酸钠，500 mM水溶液

带有核绿色标签的β2肾上腺素受体BacMam

异丙肾上腺素10 mM，溶于10 mM盐酸中

用荧光成像监测细胞核中cAMP的变化。基因编码并包装在BacMam病毒载体中，便于转导到多种细胞类型中。

Montana Molecular-cAMP部分出版参考：

J. Xu, et al. An evolutionarily conserved olfactory receptor is required for sex differences in blood pressure. Science Advances. March 2024 (bioRxiv)

J. Alvarado et al. Transient cAMP production drives rapid and sustained spiking in brainstem parabrachial neurons to suppress feeding. Neuron. February 2024. (bioRxiv)

H. Hamzeh, et al. Deciphering rapid cell signaling and control of cell motility by reverse opto-chemical engineering. bioRxiv. February 2024.

N. Philip. Fatty acid metabolism promotes TRPV4 activity in lung microvascular endothelial cells in pulmonary arterial hypertension. Lung Cellular and Molecular Physiology. January 2024.

L. Ripoll & M. von Zastrow. Spatial organization of adenylyl cyclase and its impact on dopamine signaling in neurons. bioRxiv. December 2023.

T. Richardson, Y. Pettway, et al. Human Pseudoislet System for Synchronous Assessment of Fluorescent Biosensor Dynamics and Hormone Secretory Profiles. Journal of Visualized Experiments. November 2023.

相关产品：

#U0205G Green Upward cADDis cAMP (Promoter CAG)

#D0331G Green Membrane-Targeted DAG

#U0200R Red Up cADDis cAMP Assay Kit

#U0300R Red Up DAG Assay Kit

Montana Molecular产品主要包括GPCR检测、细胞应激和毒性相关检测工具，为客户提供了长时间内观察候选药物对细胞过程影响的能力。艾美捷科技是Montana Molecular的中国代理商，为科研工作者提供优质的产品与服务。