IL-22 is a member of the IL-10 family of regulatory cytokines.Members of this family share partial homology in their amino acid sequences，but they are dissimilar in their biological functions. Produced by T lymphocytes，IL-22 inhibits IL-4 production by Th2 cells，and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-beta/CRF2-4 and IL-22R，both of which are members of the class II cytokine-receptor family.
