XTT (2,3-Bis-(2-Methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide, disodium salt) is a tetrazolium derivative used widely in cell viability and proliferation testing. The material is readily reduced in viable cells to a highly water-soluble orange colored product (λ= 475 nm). Applications of the reagent include studies of antifungal susceptibility, drug sensitivity of cells, parasitic nematode viability and tumor cell cytotoxicity. Please also see the XTT Cell Proliferation Assay Kit.
