LP01 (BP-Lipid 215) is a biodegradable ionizable lipid which can reduce liver bioaccumulation significantly compared to levels observed with non-biodegradable ionizable lipids such as MC3. These lipids can form nanoparticles that can encapsulate and deliver siRNA, mRNA, DNA or small molecules into cells. The pKa is 6.3. Reagent grade, for research use only.