THPTA is a water-soluble, very effective ligand for Cu(I)-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). It serves a dual purpose: 1) Acceleration of the CuAAC reaction by maintaining the Cu(I) oxidation state of copper sources and 2) Protection of biomolecules from oxidative damage during the labeling reaction. nTHPTA is a superior alternative to water-insoluble TBTA.n a) J. Am. Chem. Soc. 2011, 133, 17993.n b) Bioconjugate Chem. 2010, 21, 1912. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
