中文名称

N-ω-CD3-十八烷基-D-赤型-鞘氨醇

英文名字

N-omega-CD3-Octadecanoyl-D-erythro-sphingosine

供应商

Matreya

产品货号

2201-1

产品报价

￥询价/1mg

产品说明书

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购买方式

银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868

产品新闻

背景资料

This product is a well-defined ceramide containing a deuterated stearic acid acylated to the sphingosine base making it an ideal stable isotope-labeled standard for lipidomic studies using mass spectrometry. Stable isotope-labeled tracers are ideal for studies involving the metabolism and various metabolites of a lipid and can be used for the quantitative evaluation of major lipid pathways.1 Lipidomics has shown great success in the use of deuterium labeled compounds in identifying and quantifying individual molecular species by the use of tandem mass spectrometry.2 Ceramide is a fatty acid amide of sphingosine that has many important biological functions and is the precursor for many complex glycosphingolipids. Ceramide functions as a precursor in the synthesis of sphingomyelin, glycosphingolipids, and of free sphingosine and fatty acids. The sphingosine can be phosphorylated to form sphingosine-1-phosphate. Two of ceramide’s metabolites, sphingosine- 1-phosphate and glucosylceramide, produce cell proliferation and other cellular functions.3 Ceramide exerts numerous biological effects, including induction of cell maturation, cell cycle arrest, terminal cell differentiation, cell senescence, and cell death.4 Because of these effects ceramide has been investigated for its use in cancer treatment and many potential approaches to cancer therapy have been presented.5 Other effects include producing reactive oxygen in mitochondria (followed by apoptosis) and stimulating phosphorylation of certain proteins (especially mitogen activated protein). It also stimulates some protein phosphatases (especially protein phosphatase 2A) making it an important controller of protein activity.

产品描述

N-C18:0-CD3-D-erythro-Ceramide|N-Stearoyl-CD3-D-erythro-sphingosine

产品形式

该N-ω-CD3-十八烷基-D-赤型-鞘氨醇产品为固体形式

保存建议

对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明书。

其他

Matreya LLC是一家脂质生化公司，致力于开发和制造高质量的脂质和生物化学品。Matreya在化学合成以及天然产物提取和纯化方面经验丰富，生产出的产品具有最佳纯度。 Matreya产品线包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和维生素E异构体（生育酚和生育三烯酚）。专长是生产高纯度鞘氨醇、神经酰胺、硫酸酯、神经节苷脂、酶抑制剂、生育酚和生育三烯酚。是全球提供脂质产品最全的供应商之一。产品涉及生物化学、制药、微生物学、食品和农业等研究领域。

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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