长链脂肪酸甲酯混合物-Long Chain Fatty Acid Methyl Ester Mixture-标准品（生化）-艾美捷科技有限公司

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中文名称: 长链脂肪酸甲酯混合物

英文名字: Long Chain Fatty Acid Methyl Ester Mixture

供应商: Matreya

产品货号: 2011-1

产品报价: ￥询价/1mL

产品说明书: 点击查看

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背景资料: Very-long-chain fatty acids (VLCFA) consisting of 26 carbons or more comprise a small but very important group of biological lipids that are found in both plants and animals. There is relatively little known about VLCFA, especially those with more than 30 carbons, and the need for high purity standards to explore their mechanisms and processes is greatly needed. VLCFA are found in small amounts in most animal tissues and are especially abundant in the brain, skin, testis, and some glands, such as the meibomian gland. The recognition of VLCFA in human diseases has recently sparked a renewed interest in the investigation of these crucial compounds. VLCFA are implicated in several diseases and standards for the determination of the lipids associated with these diseases are needed. One of these human diseases, X-linked adrenoleukodystrophy, causes an increase in plasma of VLCFA due to a genetic defect that affects the peroxisomal assembly and contributes to severe pathological changes such as inflammatory responses; This disease can also lead to neurological changes and severe demyelination. Another disease that results in unusually high levels of VLCFA is Zwelleger syndrome which is characterized by a reduced number of, and morphologically-abnormal, peroxisomes.1 In plants VLCFA are converted to long chain hydrocarbons which are used to make waxes that are essential to their survival.2,3 VLCFA acylated to sphingolipids are critical in many biological functions4 and substantial amounts are found to be amide-linked to the long-chain sphingoid base sphinganine, forming a ceramide, which constitutes the lipid backbone of sphingomyelin and other sphingolipids. VLCFA can often be found in esterified linkages with cholesterol, gangliosides, galactocerebrosides, sphingomyelin, and phosphatidylcholine. In myelin VLCFA are important in increasing the structural stability. Lipids are very important in signaling and the influence of VLCFA in signaling needs to be further explored.5 Studies that explore the roles of VLCFA acylated to phospholipids, sphingolipids and glycerolipids or esterified to triglycerides, sterols, and other compounds show great promise in revealing much about the various biological functions of these lipids. If you require VLCFA acylated or esterified to a specific backbone the team at Matreya will be happy to synthesize them for you. Composition: Quantitative mix contains:,C24:0, 20.0%,C26:0, 20.0%,C28:0, 20.0%,C30:0, 20.0%,C32:0, 20.0%

产品描述: Long Chain Fatty Acid Methyl Ester Mixture, quantitative mixture

产品形式: A 25 mg/ml mixture in methylene chloride

保存建议: 对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明书。

其他: Matreya LLC是一家脂质生化公司，致力于开发和制造高质量的脂质和生物化学品。Matreya在化学合成以及天然产物提取和纯化方面经验丰富，生产出的产品具有最佳纯度。 Matreya产品线包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和维生素E异构体（生育酚和生育三烯酚）。专长是生产高纯度鞘氨醇、神经酰胺、硫酸酯、神经节苷脂、酶抑制剂、生育酚和生育三烯酚。是全球提供脂质产品最全的供应商之一。产品涉及生物化学、制药、微生物学、食品和农业等研究领域。