This product is the inactive methyl ester of the acyl-CoA synthase inhibitor 2-fluoropalmitic acid. 2-Fluoropalmitic acid is a synthetic inhibitor of palmitoyl-CoA formation by long chain acyl-CoA synthetase thereby inhibiting sphingosine biosynthesis and protein palmitoylation. This product is very useful in the investigation of sphingosine synthesis1, protein acylation2, and other biological mechanisms3. Other alpha-fluoro-fatty acids also inhibit their respective acyl-CoAs.4