中文名称

N-己酰基-NBD-葡萄糖基神经酰胺

英文名字

N-Hexanoyl-NBD-glucosylceramide

供应商

Matreya

产品货号

1622-1

产品报价

￥询价/1mg

产品说明书

点击查看

购买方式

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产品新闻

背景资料

This high purity fluorescent product is ideal for the identification of glucocerebrosides in samples and biological systems.1 7-nitrobenzofurazan (NBD) has been shown to have only a small influence on lipid adsorption into cells and cellular membranes. This fluorescent analog of natural glucosylceramide is comparable to C6:0-glucosylceramide in many biological functions.2 This cerebroside product is a glycosphingolipid containing a glucose attached to a ceramide (glucocerebroside) acylated with a C6:0-NBD fatty acid. Glucosylceramide is a major constituent of skin lipids where it has an important role in lamellar body formation and in maintaining the water permeability barrier. Glucocerebroside is very important due to its function as the biosynthetic precursor of lactosylceramide and from there of most of the neutral oligoglycolipids and gangliosides. Glucocerebroside is the only glycosphingolipid that is found in plants, fungi, and animals and is one of the most abundant glycosphingolipids in plants. Due to the relatively high melting point of cerebrosides (much greater than physiological body temperature) they have a para-crystalline structure. Glucocerebrosides tend to be concentrated in the outer leaflet of the plasma membrane in lipid rafts. It has been reported that glucocerebrosides are essential for the activity of tyrosinase (a key enzyme in melanin biosynthesis), to elicit defense responses in plants, and to help the plasma membrane in plants to withstand stresses brought about by cold and drought. In Gaucher’s disease glucocerebrosides accumulate in the spleen, liver, lungs, bone marrow, and brain due to a deficiency of the enzyme glucocerebrosidase.3 This accumulation of glucocerebroside has been associated with chemotherapy resistance. Glucocerebroside has been shown to be able to modulate membrane traffic along the endocytic pathway.4

产品描述

N-C6:0-NBD-beta-D-Glucosylsphingosine|N-C6:0-NBD-Glucosylceramide

产品形式

该N-己酰基-NBD-葡萄糖基神经酰胺产品为固体形式

保存建议

对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明书。

其他

Matreya LLC是一家脂质生化公司，致力于开发和制造高质量的脂质和生物化学品。Matreya在化学合成以及天然产物提取和纯化方面经验丰富，生产出的产品具有最佳纯度。 Matreya产品线包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和维生素E异构体（生育酚和生育三烯酚）。专长是生产高纯度鞘氨醇、神经酰胺、硫酸酯、神经节苷脂、酶抑制剂、生育酚和生育三烯酚。是全球提供脂质产品最全的供应商之一。产品涉及生物化学、制药、微生物学、食品和农业等研究领域。

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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