该JAK3 Polyclonal Antibody. The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
应用类型
WB,IHC-p,IF,ELISA
免疫原
Synthesized peptide derived from human JAK3 around the non-phosphorylation site of Tyr785.
