该PKC zeta Polyclonal Antibody. This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
应用类型
WB,IHC-p,IF,ELISA
免疫原
Synthesized peptide derived from human PKC ζ around the non-phosphorylation site of Thr560.
