该CD54 Polyclonal Antibody. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
应用类型
WB,IHC-p,ELISA
免疫原
Synthesized peptide derived from human ICAM-1 around the non-phosphorylation site of Tyr512.