该CREB1 Polyclonal Antibody. This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.
应用类型
WB,IHC-p,ELISA
免疫原
Synthesized peptide derived from human CREB-1 around the non-phosphorylation site of Ser133.
