该Phospho-PEA15(S104) Polyclonal Antibody. This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.
应用类型
IHC
免疫原
A synthetic phosphorylated peptide around S104 of human PEA15 (NP_003759.1).