该Phospho-eIF2α(S51) Polyclonal Antibody. Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.
应用类型
WB
免疫原
A synthetic phosphorylated peptide around S51 of human eIF2α (NP_004085.1).
