该Phospho-Jak3(Y980/981) Polyclonal Antibody. The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
应用类型
WB
免疫原
A synthetic phosphorylated peptide around Y980 of human Jak3 (NP_000206.2).
