该Phospho-Btk(Y223) Polyclonal Antibody. The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
应用类型
IF
免疫原
A synthetic phosphorylated peptide around Y223 of human Btk (NP_000052.1).
