- 中文名称
RPA1多克隆抗体
- 英文名字
- RPA1 Polyclonal Antibody
- 供应商
- Reddot Biotech
- 产品货号
- RD265722A
- 产品报价
- ￥询价/60uL ￥询价/120uL ￥询价/200uL
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- 该RPA1 Polyclonal Antibody. This gene encodes the largest subunit of the heterotrimeric Replication Protein A (RPA) complex, which binds to single-stranded DNA (ssDNA), forming a nucleoprotein complex that plays an important role in DNA metabolism, being involved in DNA replication, repair, recombination, telomere maintenance, and co-ordinating the cellular response to DNA damage through activation of the ataxia telangiectasia and Rad3-related protein (ATR) kinase. The nucleoprotein complex protects the single-stranded DNA from nucleases, prevents formation of secondary structures that would interfere with repair, and co-ordinates the recruitment and departure of different genome maintenance factors. This subunit contains four oligonucleotide/oligosaccharide-binding (OB) domains, though the majority of ssDNA binding occurs in two of these domains. The heterotrimeric complex has two different modes of ssDNA binding, a low-affinity and high-affinity mode, determined by which ssDNA binding domains are utilized. The different binding modes differ in the length of DNA bound and in the proteins with which it interacts, thereby playing a role in regulating different genomic maintenance pathways.
- 应用类型
- IF
- 免疫原
- Recombinant fusion protein of human RPA1 (NP_002936.1).
- 来源宿主
- 兔
- 反应性
- 人,小鼠
- 保存建议
- 储存于-20 ℃。 避免冻融循环。
- 其他
- Reddot Biotech是由一支拥有35年医疗管理经验团队创办的加拿大本土品牌，其已在ELISA产品线上深耕7个年头，并且仍在不断前进中。产品的质量保证也让其越来越多被“收纳进”文献当中，产品线包括ELISA试剂盒、抗体、少量生化试剂，其中ELISA试剂盒超过6000+，物种类型较多：人；大鼠；小鼠；犬科类；牛科；鱼；鸡；猪；兔；山羊；绵羊；猿；马；豚鼠等，像激素类指标促卵泡素（FSH）、促黄体激素（LH），新冠相关病毒受体ACE2、ACE以及肿瘤免疫相关的指标精氨酸酶（ARG）等已是热门应用指标。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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