- 中文名称
DMTN多克隆抗体
- 英文名字
- DMTN Polyclonal Antibody
- 供应商
- Reddot Biotech
- 产品货号
- RD217886A
- 产品报价
- ¥询价/20uL ¥询价/60uL ¥询价/120uL ¥询价/200uL

- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻

- 背景资料
- 该DMTN Polyclonal Antibody. The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms. DMTN (Dematin Actin Binding Protein) is a Protein Coding gene. Diseases associated with DMTN include Hypotrichosis and Hereditary Spherocytosis. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Miscellaneous transport and binding events. GO annotations related to this gene include receptor binding and protein self-association. An important paralog of this gene is ABLIM1.
- 应用类型
- WB,IHC,ELISA
- 免疫原
- Synthetic peptide of human DMTN
- 来源宿主
- 兔
- 反应性
- 人, 小鼠
- 保存建议
- 储存于-20 ℃。 避免冻融循环。
- 其他
- Reddot Biotech是由一支拥有35年医疗管理经验团队创办的加拿大本土品牌,其已在ELISA产品线上深耕7个年头,并且仍在不断前进中。产品的质量保证也让其越来越多被“收纳进”文献当中,产品线包括ELISA试剂盒、抗体、少量生化试剂,其中ELISA试剂盒超过6000+,物种类型较多:人;大鼠;小鼠;犬科类;牛科;鱼;鸡;猪;兔;山羊;绵羊;猿;马;豚鼠等,像激素类指标促卵泡素(FSH)、促黄体激素(LH),新冠相关病毒受体ACE2、ACE以及肿瘤免疫相关的指标精氨酸酶(ARG)等已是热门应用指标。

- 注意
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