- 中文名称
CGAS多克隆抗体
- 英文名字
- CGAS Polyclonal Antibody
- 供应商
- Reddot Biotech
- 产品货号
- RD217843A
- 产品报价
- ¥询价/20uL ¥询价/60uL ¥询价/120uL ¥询价/200uL

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- 该CGAS Polyclonal Antibody. Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. Catalysis involves both the formation of a 2',5' phosphodiester linkage at the GpA step and the formation of a 3',5' phosphodiester linkage at the ApG step, producing c[G(2',5')pA(3',5')p]. Has antiviral activity by acting as a key cytosolic DNA sensor, the presence of double-stranded DNA (dsDNA) in the cytoplasm being a danger signal that triggers the immune responses. Binds cytosolic DNA directly, leading to activation and synthesis of cGAMP, a second messenger that binds to and activates TMEM173/STING, thereby triggering type-I interferon production. cGAMP can be transferred between cells by virtue of packaging within viral particles contributing to IFN-induction in newly infected cells in a cGAS-independent but TMEM173/STING-dependent manner (PubMed:26229115).
- 应用类型
- WB,ELISA
- 免疫原
- Synthetic peptide of human MB21D1
- 来源宿主
- 兔
- 反应性
- 人
- 保存建议
- 储存于-20 ℃。 避免冻融循环。
- 其他
- Reddot Biotech是由一支拥有35年医疗管理经验团队创办的加拿大本土品牌,其已在ELISA产品线上深耕7个年头,并且仍在不断前进中。产品的质量保证也让其越来越多被“收纳进”文献当中,产品线包括ELISA试剂盒、抗体、少量生化试剂,其中ELISA试剂盒超过6000+,物种类型较多:人;大鼠;小鼠;犬科类;牛科;鱼;鸡;猪;兔;山羊;绵羊;猿;马;豚鼠等,像激素类指标促卵泡素(FSH)、促黄体激素(LH),新冠相关病毒受体ACE2、ACE以及肿瘤免疫相关的指标精氨酸酶(ARG)等已是热门应用指标。

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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