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中文名称

HERPUD1 抗体

英文名字
HERPUD1 Antibody
供应商
ProSci
产品货号
PSI-59-043
产品报价
¥询价/400ul
产品说明书
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产品新闻
背景资料
The accumulation of unfolded proteins in the endoplasmicnreticulum (ER) triggers the ER stress response. This responsenincludes the inhibition of translation to prevent furthernaccumulation of unfolded proteins, the increased expression ofnproteins involved in polypeptide folding, known as the unfoldednprotein response (UPR), and the destruction of misfolded proteinsnby the ER-associated protein degradation (ERAD) system. This genenmay play a role in both UPR and ERAD. Its expression is induced bynUPR and it has an ER stress response element in its promoter regionnwhile the encoded protein has an N-terminal ubiquitin-like domainnwhich may interact with the ERAD system. This protein has beennshown to interact with presenilin proteins and to increase thenlevel of amyloid-beta protein following its overexpression.nAlternative splicing of this gene produces multiple transcriptnvariants, some encoding different isoforms. The full-length naturenof all transcript variants has not been determined. [provided bynRefSeq].
应用类型
WB
免疫原
This HERPUD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human HERPUD1.
来源宿主
反应性
保存建议
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
其他
ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。
注意
该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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