- 中文名称
CYP2D6 抗体
- 英文名字
- CYP2D6 Antibody
- 供应商
- ProSci
- 产品货号
- PSI-57-786
- 产品报价
- ¥询价/400ul

- 产品说明书
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- 产品新闻

- 背景资料
- This gene encodes a member of the cytochrome P450nsuperfamily of enzymes. The cytochrome P450 proteins arenmonooxygenases which catalyze many reactions involved in drugnmetabolism and synthesis of cholesterol, steroids and other lipids.nThis protein localizes to the endoplasmic reticulum and is known tonmetabolize as many as 20% of commonly prescribed drugs. Itsnsubstrates include debrisoquine, an adrenergic-blocking drug;nsparteine and propafenone, both anti-arrythmic drugs; andnamitryptiline, an anti-depressant. The gene is highly polymorphicnin the population; certain alleles result in the poor metabolizernphenotype, characterized by a decreased ability to metabolize thenenzyme's substrates. The gene is located near two cytochrome P450npseudogenes on chromosome 22q13.1. Alternatively spliced transcriptnvariants encoding different isoforms have been found for this gene.
- 应用类型
- WB, IHC-P
- 免疫原
- This CYP2D6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the N-terminal region of human CYP2D6.
- 来源宿主
- 兔
- 反应性
- 人
- 保存建议
- Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。

- 注意
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