- 中文名称
ERCC1 抗体
- 英文名字
- ERCC1 Antibody
- 供应商
- ProSci
- 产品货号
- PSI-57-479
- 产品报价
- ￥询价/400ul
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- The product of this gene functions in the nucleotidenexcision repair pathway, and is required for the repair of DNAnlesions such as those induced by UV light or formed bynelectrophilic compounds including cisplatin. The encoded proteinnforms a heterodimer with the XPF endonuclease (also known asnERCC4), and the heterodimeric endonuclease catalyzes the 5'nincision in the process of excising the DNA lesion. Thenheterodimeric endonuclease is also involved in recombinational DNAnrepair and in the repair of inter-strand crosslinks. Mutations innthis gene result in cerebrooculofacioskeletal syndrome, andnpolymorphisms that alter expression of this gene may play a role inncarcinogenesis. Multiple transcript variants encoding differentnisoforms have been found for this gene. The last exon of this genenoverlaps with the CD3e molecule, epsilon associated protein gene onnthe opposite strand.
- 应用类型
- WB
- 免疫原
- This ERCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-297 amino acids from the C-terminal region of human ERCC1.
- 来源宿主
- 兔
- 反应性
- 人, 小鼠
- 保存建议
- Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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