- 中文名称
UGT1A1 抗体
- 英文名字
- UGT1A1 Antibody
- 供应商
- ProSci
- 产品货号
- PSI-57-373
- 产品报价
- ¥询价/400ul

- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻

- 背景资料
- This gene encodes a UDP-glucuronosyltransferase, an enzymenof the glucuronidation pathway that transforms small lipophilicnmolecules, such as steroids, bilirubin, hormones, and drugs, intonwater-soluble, excretable metabolites. This gene is part of ancomplex locus that encodes several UDP-glucuronosyltransferases.nThe locus includes thirteen unique alternate first exons followednby four common exons. Four of the alternate first exons arenconsidered pseudogenes. Each of the remaining nine 5' exons may benspliced to the four common exons, resulting in nine proteins withndifferent N-termini and identical C-termini. Each first exonnencodes the substrate binding site, and is regulated by its ownnpromoter. The preferred substrate of this enzyme is bilirubin,nalthough it also has moderate activity with simple phenols,nflavones, and C18 steroids. Mutations in this gene result innCrigler-Najjar syndromes types I and II and in Gilbert syndrome.
- 应用类型
- WB, IHC-P, IF
- 免疫原
- This UGT1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-90 amino acids from the N-terminal region of human UGT1A1.
- 来源宿主
- 兔
- 反应性
- 人
- 保存建议
- Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。

- 注意
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