- 中文名称
HTR2C 抗体
- 英文名字
- HTR2C Antibody
- 供应商
- ProSci
- 产品货号
- PSI-57-337
- 产品报价
- ¥询价/400ul

- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻

- 背景资料
- Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter,nelicits a wide array of physiological effects by binding to severalnreceptor subtypes, including the 5-HT2 family ofnseven-transmembrane-spanning, G-protein-coupled receptors, whichnactivate phospholipase C and D signaling pathways. This genenencodes the 2C subtype of serotonin receptor and its mRNA isnsubject to multiple RNA editing events, where genomically encodednadenosine residues are converted to inosines. RNA editing isnpredicted to alter amino acids within the second intracellular loopnof the 5-HT2C receptor and generate receptor isoforms that differnin their ability to interact with G proteins and the activation ofnphospholipase C and D signaling cascades, thus modulatingnserotonergic neurotransmission in the central nervous system.nStudies in humans have reported abnormalities in patterns of 5-HT2Cnediting in depressed suicide victims.
- 应用类型
- WB
- 免疫原
- This HTR2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the Central region of human HTR2C.
- 来源宿主
- 兔
- 反应性
- 人
- 保存建议
- Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。

- 注意
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