- 中文名称
HLA-DRB4 抗体
- 英文名字
- HLA-DRB4 Antibody
- 供应商
- ProSci
- 产品货号
- PSI-57-203
- 产品报价
- ￥询价/400ul
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- HLA-DRB4 belongs to the HLA class II beta chainnparalogues. This class II molecule is a heterodimer consisting ofnan alpha (DRA) and a beta (DRB) chain, both anchored in thenmembrane. It plays a central role in the immune system bynpresenting peptides derived from extracellular proteins. Class IInmolecules are expressed in antigen presenting cells (APC: Bnlymphocytes, dendritic cells, macrophages). The beta chain isnapproximately 26-28 kDa and its gene contains 6 exons. Exon onenencodes the leader peptide, exons 2 and 3 encode the twonextracellular domains, exon 4 encodes the transmembrane domain andnexon 5 encodes the cytoplasmic tail. Within the DR molecule thenbeta chain contains all the polymorphisms specifying the peptidenbinding specificities. Typing for these polymorphisms is routinelyndone for bone marrow and kidney transplantation. DRB1 is expressednat a level five times higher than its paralogues DRB3, DRB4 andnDRB5. The presence of DRB4 is linked with allelic variants of DRB1,notherwise it is omitted. There are 4 related pseudogenes: DRB2,nDRB6, DRB7, DRB8 and DRB9.
- 应用类型
- WB
- 免疫原
- This HLA-DRB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-72 amino acids from the N-terminal region of human HLA-DRB4.
- 来源宿主
- 兔
- 反应性
- 人
- 保存建议
- Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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