MB 680R DBCO is a bright and very photostable probe used for imaging of azide-containing biomolecules without the need for copper catalyst. MB 680R DBCO reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. In application where the presence of copper is a concern MB 680R DBCO is an ideal alternative to copper requiring fluorescent alkynes.nnMB 680R is a bright and photostable near IR dye that emits fluorescence at about 700 nm in the borderline spectral region between far-red and near-IR. MB 680R dye is water soluble and pH-insensitive from pH 4 to pH 10. MB 660R is a rhodamine-based dye, and like rhodamine dyes in general, it is very bright and exceptionally photostable . The superior photostability and excellent brightness of MB 680R makes this dye an ideal for confocal microscopy, single molecule imaging and other applications that demand both brightness and photostability.nnnMB 660R dye spectrally is almost identical to CF® 680R Dye and can be used a less expensive alternative to these dyes.nnMB 660R DBCO reagent is not suitable for staining intracellular components of fixed and permeabilized cells due to high backgrounds.nnCF® Dye is a registered trademark of Biotium.
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Click Chemistry Tools(CCT)公司位于美国亚利桑那州斯科茨代尔(Scottsdale,AZ)。自公司成立以来,一致致力于不断开发和扩展一系列连接产品。他们利用特别新的研究成果研发生产出新颖的交联和标记试剂。产品被广泛用于药物研发、癌症治疗以及各类诊断技术等。此外,CCT还可以提供个性化的定制产品,已满足不同用户的需求。目前CCT的产品线主要包括:Azides(Biotin-Azides)试剂、Bis-sulfone交联试剂、DBCO试剂、TCO试剂、Terminal Alkyne试剂、Tetrazine试剂、标记试剂盒以及分选用底物等。nFluoroprobes公司位于美国亚利桑那州斯科茨代尔(Scottsdale, AZ),自成立以来,一直致力于不断开发一系列的连接(linker)产品。利用特别新的研究成果研发生产出各类新颖的交联和标记试剂。其产品被广泛用于药物研发与筛选、疾病治疗方法和诊断技术等领域。此外,Fluoroprobes还可以根据客户的个性化需求提供各类定制连接产品。代表产品有Classic Fluorescent Dyes, AZDye, Cyanine Dyes, IR Dyes, MB dyes以及一些标记试剂盒等。nQuanta Biodesign公司位于美国中部的俄亥俄州,成立于1997年。也是专注于生产研发各类标记产品的品牌之一。其研发的产品与dPEG技术相结合,生产出他们独有的专利产品dPEG Building Blocks and Linkers,被广泛用于细胞治疗和分子诊断等研究领域。另外,还可为广大科研工作者提供多种化学修饰试剂以及传统Liner等。n目前上述三个品牌都已被被Vectorlabs收购并整合到Vectorlabs产品中