- 中文名称
TTA-A2（5毫克）
- 英文名字
- TTA-A2
- 供应商
- Alomone
- 产品货号
- ALO-T-140-5
- 产品报价
- ￥已停产
- 产品说明书
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- 产品新闻
- 背景资料
- TTA-A2 was found to inhibit all three subtypes of low-voltage-gated T-type channels (CaV3.1, CaV3.2, and CaV3.3) with comparable potencies. Changing membrane resting potentials from −100 to −80 mV enhanced compound potency by ∼40-fold, from an IC50 of ∼4 μM to 0.1 μM, respectively, indicating state dependence of inhibition. in vivo studies have demonstrated that TTA-A2 reduces absence epilepsy seizures, pain perception, nicotine self-administration and weight gain. It also improves the quality of sleep and displays antipsychotic properties.
- 产品描述
- A Blocker of T-type CaV Channels
- 产品形式
- Low-voltage-activated (T-type/Cav3) Ca2+ channels are a subclass of voltage-dependent Ca2+ channels allowing Ca2+ entry near the resting potential of most cells. Various synthetic T-channel blockers have been described in the past few years including TTA-A2, a potent and state-dependent, and highly selective T-type CaV antagonist.
- 保存建议
- 艾美捷为您提供的Alonmone Labs原装进口的TTA-A2 (5 mg)产品可室温运输，建议您在收到产品后将其置于合适的温度下保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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