Compound 56 is a highly potent inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 0.006 nM).{28435} It has been used to inhibit EGFR activity in pancreatic cancer cell lines and to induce the differentiation of rat mesenchymal stem cells.{28436,28437}
产品描述
A highly potent inhibitor of the tyrosine kinase activity of EGFR (IC50 = 0.006 nM); inhibits EGFR activity in pancreatic cancer cell lines and induces the differentiation of rat mesenchymal stem cells