The MLL complex methylates histone 3 at lysine 4 (H3K4) to upregulate transcription. MLL1 is the catalytic subunit which exhibits a low basal methyltransferase activity. Addition of WDR5, Ash2L, and RbBP5 (WAR) enhances Histone H3K4 methylation 300-fold;
产品描述
提供的MLL1/WAR复合物(人源重组蛋白)(100 ug)产品形式为:Four tubes containing protein sufficient to form an equimolar ratio of the MLL1/WAR complex
产品形式
The MLL complex methylates histone 3 at lysine 4 H3K4 to upregulate transcription. MLL1 is the catalytic subunit which exhibits a low basal methyltransferase activity. Addition of WDR5 Ash2L and RbBP5 WAR enhances Histone H3K4 methylation 300-fold