Cytoskeleton 超值大促，助力小 G 蛋白研究！

发布者：艾美捷科技发布时间：2020-03-10

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常闻三月之春光秀丽兮，

万物始以惊蛰；

故特推 Cytoskeleton 之促销兮，

回馈以尊敬之顾客。

即日至谷雨兮，

巧推超值产品以示诚意也；

艾美捷设巨惠小 G 蛋白产品线以大促兮，

折扣包您满意也。

吾不多言语 Cytoskeleton 众多大促产品兮，

请您阅具体下文也。

为答谢和回馈广大科研工作者们长期以来对武汉艾美捷科技有限公司的大力支持，艾美捷科技联合细胞骨架领域顶级供应商 Cytoskeleton 联合推出：小 G 蛋白产品线超值大促，一年仅此一次，千万不要错过啊！本次促销活动产品涵盖 GEFs, 小 G 蛋白和 G-LISA 活化试剂盒等。

小 G 蛋白(Small G Protein)因分子量只有 20—30KD 而得名，同时具有 GTP 酶活性，在细胞信号通路中发挥分子开关的功能，参与调控很多生物学过程，包括分泌活动和细胞骨架的装配等。目前发现的小 G 蛋白包括 Rho, Rac, Arf1 & 6, Ras, Ral 等。小 G 蛋白的共同特点是，当结合了 GTP 时即成为活化形式，这时可作用于下游分子使之活化，而当 GTP 水解成为 GDP 时（自身为 GTP 酶）则恢复到非活化状态。

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Pull-down 和 G-LISA 实验都被广泛地用于研究小 G 蛋白的活性。Pull-down 实验又叫蛋白质体外结合实验，可用于测定活性的 GTPase 亚型，可作为对 G-LISA 实验的补充。G-LISA 实验是一种改进的 ELISA，可测定 3-D 细胞系、原代细胞裂解液及组织裂解液中有活性的 GTPase，使 GTPase 定量的准确性增加。

活动详情：

时间：即日起-2020 年 4 月 22 日

对象：仅限中国区终端客户

品目：GEFs, 小 G 蛋白和 G-LISA 活化试剂盒等产品（详情见下方活动品目列表）

内容：直享 6.5 折超低优惠！

活动品目列表：

货号	产品名称	规格	目录价	促销价
ACD03	Anti-Cdc42 Mouse Monoclonal Antibody	2x200ul	5590	3634
ACD03-S	Anti-Cdc42 Mouse Monoclonal Antibody (sample size)	1x50ul	1572	1022
ARC03	Anti-Rac1 specific mouse MAb	2x100ul	5590	3634
ARC03-S	Anti-Rac1 specific mouse MAb(sample size)	1x25ul	1572	1022
ARH05	Anti-RhoA antibody (mouse MAb) + control.	2x200ul	5590	3634
ARH05-S	Anti-RhoA antibody (mouse MAb) + control. (Trial size)	1x50ul	1572	1022
BK008	Ras Activation Assay Biochem Kit	KIT50assays	11326	7362
BK008-S	Ras Activation Assay Biochem Kit	KIT20assays	5752	3739
BK030	Combo RhoA/Rac1/Cdc42 Activation Assay Kit	KIT3x10assays	14988	9742
BK032-S	Arf1 Pulldown Activation Assay Kit	KIT20assays	6886	4476
BK033-S	Arf6 Pulldown Activation Assay Kit	KIT20assays	6886	4476
BK034	Cdc42 Pulldown Activation Assay Kit	KIT50assays	11326	7362
BK034-S	Cdc42 Pulldown Activation Assay Kit	KIT20assays	5752	3739
BK035	Rac1 Pulldown Activation Assay Kit	KIT50assays	11326	7362
BK035-S	Rac1 Pulldown Activation Assay Kit	KIT20assays	5752	3739
BK036	RhoA Pulldown Activation Assay Kit	KIT80assays	11326	7362
BK036-S	RhoA Pulldown Activation Assay Kit	KIT20assays	5752	3739
BK040	RalA Activation Assay Biochem Kit	KIT50assays	11326	7362
BK100	GEF Exchange Assay	KIT60-300assays	10451	6793
BK105	GAP Assay Kit	KIT80-160assays	10451	6793
BK121	RhoA G-LISA Activation Assay (luminescence)	KIT96assays	14097	9163
BK124	RhoA G-LISA Activation Assay (absorbance)	KIT96assays	14097	9163
BK124-S	RhoA G-LISA Activation Assay (absorbance)	KIT24assays	8507	5529
BK125	Rac1,2,3 G-LISA Activation Assay Kit	KIT96assays	14097	9163
BK126	Rac1 G-LISA Activation Assay Kit	KIT96assays	14097	9163
BK127	Cdc42 G-LISA Activation Assay Kit	KIT96assays	14097	9163
BK127-S	Cdc42 G-LISA Activation Assay Kit	KIT24assays	8507	5529
BK128	Rac1 G-LISA Activation Assay Kit	KIT96assays	14097	9163
BK128-S	Rac1 G-LISA Activation Assay Kit	KIT24assays	8507	5529
BK129	RalA G-LISA Activation Assay Kit	KIT96assays	14097	9163
BK131	Ras G-LISA Activation Assay Kit	KIT96assays	14097	9163
BK132	Arf1 G-LISA Activation Assay Kit	KIT96assays	14097	9163
BK133	Arf6 G-LISA Activation Assay Kit	KIT96assays	14097	9163
BK135	G-LISA Bundle (BK135 = BK124-S + BK127-S + BK128-S)	3KITS(24assays/kit)	23495	15272
BK150	RhoA ELISA Kit	KIT96assays	7697	5003
C17G01-A	Cdc42-GST protein: dominant negative	1x25ug	4213	2738
C6101-A	Cdc42-His Protein: constituitively active	1x10ug	4213	2738
CD01-A	Cdc42-His Protein: Wild type	1x100ug	4213	2738
CD01-C	Cdc42-His Protein: Wild type	3x100ug	10289	6688
CD01-XL	Cdc42-His Protein: Wild type	1x1mg	21874	14218
CDG01-C	Cdc42-GST Protein: Wild type	8x25ug	7859	5108
CN01-A	Rho Activator	5x10units	3224	2096
CN01-B	Rho Activator	20x10units	11747	7636
CN02-A	Rac and Cdc42 Activator	5x10units	3224	2096
CN02-B	Rac and Cdc42 Activator	20x10units	11747	7636
CN03-A	Rho activator II	3x20ug	3224	2096
CN03-B	Rho activator II	9x20ug	9074	5898
CN04-A	Rho/Rac/Cdc42 Activator I	3x20ug	3224	2096
CN04-B	Rho/Rac/Cdc42 Activator I	9x20ug	9074	5898
CS-GE03	Ras-GRF GEF protein (human recomb. CDC25 domain, MBP tagged)	1x100ug	5590	3634
CS-GE04	Tiam1 GEF protein (human recomb. DHPH domain, MBP tagged)	1x100ug	5590	3634
CS-GE05	Vav1 GEF protein (human recomb. DHPHC1 domain Y174D mutant, 6xHis tagged)	1x100ug	5590	3634
CS-GE06	Vav2 GEF protein (human recomb. DH domain, 6xHis tagged)	1x100ug	5590	3634
CS-GE07	ARNO Protein: GEF (Sec7) domain (aa31- 267, human recomb., 6xHis tagged)	1x100ug	5590	3634
CS-GE08	SOS2 exchange domain (563-1051) protein (Human recombinant)	1x100ug	5590	3634
CS-GE09	RAPGEF5 Protein: Ras association and exchange domain (57– 580) wild type. (Human recombinant, GST tagged)	1x100ug	5590	3634
CS-RS02	N-Ras Protein; wild-type (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS03	K-Ras4B Protein: wild-type (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS04	K-Ras4B Mutant Protein: G12V (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS05	R-Ras Protein: wild-type (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS06	K-Ras4B Mutant Protein: G13D (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS07	K-Ras4B Mutant Protein: G13S (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS08	K-Ras4B Mutant Protein: K128A (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS09	K-Ras4B Mutant Protein: Q61P (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS10	K-Ras4B Mutant Protein: R135A (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS11	K-Ras4B Mutant Protein: G12D+I36N (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS12	K-Ras4B Mutant Protein: G12D+D38A (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CS-RS13	K-Ras4B Mutant Protein: G12D (human recombinant with 6xHis-tag)	1x100ug	6238	4055
CT03-A	C3 transferase protein	1x25ug	3224	2096
CT03-C	C3 transferase protein	4x25ug	11261	7320
CT04-A	Cell Permeable Rho Inhibitor (C3 Trans based))	1x20ug	3224	2096
CT04-B	Cell Permeable Rho Inhibitor (C3 Trans based))	5x20ug	9641	6267
CT04-C	Cell Permeable Rho Inhibitor (C3 Trans based))	20x20ug	25520	16588
GAP01-A	Rho GAP Protein GST	1x50ug	4456	2896
GAP01-B	Rho GAP Protein GST	4x50ug	10937	7109
GAS01-A	Rho GAP Protein: catalytic domain GST	1x50ug	4456	2896
GAS01-B	Rho GAP Protein: catalytic domain GST	4x50ug	10937	7109
GDI01-A	GDP dissociation inhibitor protein GST fusion	1x25ug	4456	2896
GE01-A	Dbs protein GEF domain - HIS fusion	2x50ug	4456	2896
GE02	SOS1 Ras GEF protein (human recomb. ExD domain, 6xHis tagged)	1x100ug	5266	3423
GE02-XL	SOS1 Ras GEF protein (human recomb. ExD domain, 6xHis tagged)	1x1mg	26735	17378
GGA07-A	GGA3-PBD Arf Affinity Beads	1x500ug	6886	4476
PAK01-A	PAK Rac1/Cdc42 binding domain protein	1x250ug	6076	3950
PAK01-B	PAK Rac1/Cdc42 binding domain protein	4x250ug	16122	10479
PAK02-A	PAK Beads, Rac1/Cdc42 binding domain protein on beads	1x500ug	7048	4581
PAK02-B	PAK Beads, Rac1/Cdc42 binding domain protein on beads	4x500ug	21550	14008
R17G01-A	Rac1 GST Protein: dominant negative	1x25ug	4213	2738
R6101-A	Rac1 His Protein: constitutively active	1x10ug	4213	2738
R6301-A	RhoA His Protein: constitutively active	1x10ug	4213	2738
RC01-A	Rac1 His Protein: wild type	1x100ug	4618	3002
RC01-C	Rac1 His Protein: wild type	3x100ug	10937	7109
RC01-XL	Rac1 His Protein: wild type	1x1mg	21874	14218
RC02-A	Rac2 His Protein: wild type	1x100ug	4618	3002
RCG01-C	Rac1 GST Protein: wild type	8x25ug	7859	5108
RF02-A	Raf protein ras binding domain on GST beads	1x2mg	7534	4897
RF02-B	Raf protein ras binding domain on GST beads	4x2mg	21874	14218
RH01-A	RhoA His Protein: wild type	1x100ug	4618	3002
RH01-C	RhoA His Protein: wild type	3x100ug	10937	7109
RH01-XL	RhoA His Protein: wild type	1x1mg	21874	14218
RH03-A	RhoC His Protein: wild type	1x100ug	4618	3002
RHG01-C	RhoA GST Protein: wild type	8x25ug	7859	5108
RR02-A	Rap1b protein (Human wild type, His)	1x100ug	4618	3002
RS01-A	H-Ras Protein; wild type 6xHis Tag	1x100ug	4618	3002
RS01-C	H-Ras Protein; wild type 6xHis Tag	3x100ug	10937	7109
RT01-A	Rhotekin RBD protein GST fusion	1x500ug	6886	4476
RT02-A	Rhotekin RBD protein on GST beads	2x2mg	9155	5951
RT02-B	Rhotekin RBD protein on GST beads	6x2mg	21874	14218
VCG03-A	VCA domain of WASP (GST fusion)	1x500ug	7697	5003

* 本活动最终解释权归艾美捷科技所有

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